The Indian blood group system (In) is a classification of blood based on the presence or absence of inherited antigens that reside within the CD44 molecule that is expressed on the surface of blood cells.[1] It is named so because 4% of the population in India possess it.[2] Most individuals express the Inb antigen that results from an arginine residue at position 46 of CD44 . The Ina blood type results from a substitution proline for arginine at this same position.
References
edit- ^ Telen MJ, Udani M, Washington MK, Levesque MC, Lloyd E, Rao N (March 1996). "A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding". J. Biol. Chem. 271 (12): 7147–53. doi:10.1074/jbc.271.12.7147. PMID 8636151.
- ^ "Red Cell Antigens - Fun Facts, Questions, Answers, Information". Fun Trivia. Archived from the original on 2015-03-12. Retrieved 2014-01-03.
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