Wikipedia

Breakthrough T1D

(Redirected from JDRF (formerly known as the Juvenile Diabetes Research Foundation))

Breakthrough T1D (formerly JDRF) is a type 1 diabetes (T1D) research and advocacy organization.

Breakthrough T1D
FoundedMay 28, 1970; 54 years ago (1970-05-28)[1]
FounderLee Ducat, Carol Lurie
23-1907729[2]
Legal status501(c)(3) nonprofit organization[3]
Location
  • New York, New York, US
MethodResearch funding,
Political advocacy,
Education
Revenue (2023)
$224 million[4]
Websitebreakthrought1d.org
Formerly called
Juvenile Diabetes Foundation (JDF) 1970 - 2012
Juvenile Diabetes Research Foundation (JDRF) 2012 - 2024[5]

Breakthrough T1D funds research for the development of new therapies and treatments for type 1 diabetes. The organization advocates for federal research funding toward new technologies and treatments and works with regulatory and policy officials to disburse funds. Breakthrough T1D also has partnerships with academia, industry, and clinicians to accelerate research into potential cures for T1D.[6]

The organization has been described as "the leading global organization funding T1D research".[7]

History

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Breakthrough T1D was founded in 1970 by a group of parents of children living with type 1 diabetes.[8] The founding members formed the organization with the intent to find a cure for type 1 diabetes and its complications by supporting research. It adopted what was at the time a novel organizational structure, where non-experts participated in developing research and advocacy policies.[8]

The creation of international affiliates followed:


In 2012, JDF changed its name to Juvenile Diabetes Research Foundation, which was later shortened to JDRF.[13]

In 2019, JDRF International appointed its first-ever CEO and President with Type 1 Diabetes, Dr. Aaron Kowalski.[14]

In 2024, the organization changed its name from JDRF to Breakthrough T1D, reflecting its focus on helping people of all ages and in line with growing awareness that T1D affects people of all ages.[15]

Research

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Breakthrough T1D supports two main research objectives:

  • Cure T1D by restoring the body’s ability to make insulin and stopping T1D before it occurs or providing insulin independence through replacement with insulin-producing cells.
  • Improve lives by minimizing the effects of T1D as much as possible until new T1D resources, technologies, and therapies are discovered.[16]

Breakthrough T1D prioritizes four strategic research areas; autoimmune therapies, cell therapies, prevention of complications, and glucose control.[17]

Artificial Pancreas (AP) Systems

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In 2006, Breakthrough T1D launched the Artificial Pancreas Consortium, allocating $6 million in grants to investigate the benefits of technology controlling blood-glucose levels to accelerate the availability of the artificial pancreas (AP). AP systems integrate three components—a CGM, an insulin pump, and an algorithm— to measure blood sugar, then calculate and administer, or withhold, insulin with minimal user input.[18]

Funding and revenue

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In 2023, Breakthrough T1D raised $224 million; of this, 78% went toward programs including research funding, 15% was spent on fundraising, and 7% was spent on administrative costs.[19] Cumulatively, Breakthrough T1D was funding approximately $568 million in T1D research projects worldwide in 2018.[20]

 
 
The images above provide an overview of Breakthrough T1D (formally known as JDRF) research spending from 2001 to 2018. [21][22]

Noted philanthropists

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See also

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References

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  1. ^ "JDRF International". Pennsylvania Department of State. Retrieved September 27, 2017.
  2. ^ "Form 990: Return of Organization Exempt from Income Tax". JDRF International. Guidestar. June 30, 2016.
  3. ^ "Exempt organization business income tax return" (PDF). irs.gov. Retrieved 28 October 2024.
  4. ^ Roberts, Brandon; Suozzo, Andrea; Glassford, Alec; Ngu, Ash (2013-05-09). "Breakthrough T1 D - Nonprofit Explorer". ProPublica. Retrieved 2024-10-28.
  5. ^ Fletcher, Stephen (2017-11-02). "JDF Rides the "Choo Choo" – History on the Hill". Retrieved 2024-10-28.
  6. ^ "Breakthrough T1D charity review & reports by Give.org". Give.org | BBB Wise Giving Alliance. Retrieved 2024-10-28.
  7. ^ "JDRF". www.delts.org. Retrieved 2024-10-29.
  8. ^ a b Nierras, Concepcion R.; Atkinson, Mark A.; Goldstein, Robert A. (1 July 2010). "The Juvenile Diabetes Research Foundation at Forty: Updates of Research in Type 1 Diabetes". Diabetes. 59 (7): 1575–1577. doi:10.2337/db10-0622. PMC 2889754. PMID 20587801. Retrieved 2024-10-28.
  9. ^ "Defining Moments in Canadian History - 100 Years of Insulin". Defining Moments Canada. Retrieved 2024-10-29.
  10. ^ "Juvenile Diabetes Research Foundation Canada". Charity Intelligence. Retrieved 2024-10-29.
  11. ^ "JDRF Australia". Australia Charities and Not-For-Profits Commission. Retrieved 2024-10-29.
  12. ^ "Diabetes charity changes name as part of global rebrand". www.civilsociety.co.uk. Retrieved 2024-10-29.
  13. ^ "Type 1 Diabetes Group Grows Up: JDRF Now 'Breakthrough T1D'". Medscape. Retrieved 2024-10-29.
  14. ^ Piemonte, Lorenzo (11 April 2019). "New JDRF CEO is first with type 1 diabetes". Diabetes Voice. Retrieved 2024-10-29.
  15. ^ "Diabetes charity changes name as part of global rebrand". www.civilsociety.co.uk. Retrieved 2024-10-29.
  16. ^ "Breakthrough T1D". International Diabetes Federation. Retrieved 2024-10-29.
  17. ^ Insel, Richard A.; Deecher, Darlene C.; Brewer, Jeffrey (2012-01-01). "Juvenile Diabetes Research Foundation: Mission, Strategy, and Priorities". Diabetes. 61 (1): 30–35. doi:10.2337/db11-1398. ISSN 0012-1797. PMC 3237656. PMID 22187372.
  18. ^ Hovorka, Roman; E Wilinska, Malgorzata; J Chassin, Ludovic; L Acerini, Carlo; B Dunger, David (March 2007). "The artificial pancreas: making headway". Practical Diabetes International. 24 (2): 56–58. doi:10.1002/pdi.1051.
  19. ^ "Breakthrough T1D charity review & reports by Give.org". Give.org | BBB Wise Giving Alliance. Retrieved 2024-10-28.
  20. ^ "JDRF | Hypo-RESOLVE". hypo-resolve.eu. Retrieved 2024-10-28.
  21. ^ Tigas, Mike; We, Sisi; Schwencke, Ken; Roberts, Brandon; Glassford, Alec (9 May 2013). "Jdrf International - Nonprofit Explorer". ProPublica. Retrieved 2024-10-28.
  22. ^ "2017 JDRF Research Grant Spending Remains at Decade Lows : 2018 Reports : Archives Reports : Report Library : Publications : Juvenile Diabetes Cure Alliance (JDCA)". www.thejdca.org. Retrieved 2024-10-28.
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