Jalal Khan refers to:
- Jalal Khan, a legendary figure in the history of Balochistan
- Jalal Khan (Bahmani rebel), who rebelled against the Bahmani Sultanate and established a shortlived state at Nalgonda
- Jalal Khan Orakzai, Afghan hero who saved the lives of thousands of Muslims of India
- Jalal Khan, Balochistan, a town in Pakistan
- Jalal Khan (athlete) (born 1927), a Pakistani javelin thrower
- Ahmad Shah II (r. 1451–1458), born Jalal Khan, ruler of the Gujarat Sultanate in India
- Diler Khan Daudzai, born Jalal Khan, Afghan General of Aurangzeb and Mughal Governor of Awadh