John and Yoko, or John & Yoko, generally refers to the relationship between John Lennon and Yoko Ono.
It may also refer to:
- "John & Yoko", the first side of Lennon and Ono's Wedding Album
- John and Yoko: A Love Story, 1985 American television biopic
- John & Yoko: Above Us Only Sky, 2018 documentary film