John Greene may refer to:
- John Greene (settler) (1597–1658), early settler and co-founder of Warwick, Rhode Island
- John Greene Jr. (1620–1708), deputy governor of Rhode Island (1690–1700)
- John Greene (American football) (1920–2010), American professional football player
- John Greene (Medal of Honor) (fl. 1862), American Civil War sailor and Medal of Honor recipient
- John Greene (Kilkenny MP) (died 1883), Irish Member of UK Parliament
- John P. Greene (1793–1844), early leader in the Latter Day Saint movement
- John L. Greene (Ohio politician) (1806–1879), American politician, judge and lawyer
- John Thomas Greene Jr. (1929–2011), U.S. federal judge
- John Greene (American politician), American politician who served in the Arizona State Senate
- John William Greene (1876–1959), Australian politician
- John Greene, Canadian politician who led the Newfoundland and Labrador New Democratic Party from 1977 to 1980
- John Edmund Greene (1894–1918), Canadian WWI pilot
- John Holden Greene (1777–1850), Federal Period architect Providence, Rhode Island
- John L. Greene (1912-1995), American screenwriter
- John M. Greene (1928–2007), American theoretical physicist and applied mathematician
- John Nassau Greene (fl. 1938), Irish politician
- John Robert Greene (born 1955), professor of American history
- John Beasley Greene (1832–1856), Egyptologist
- John C. Greene (1926–2016), American dentist and public health administrator
- John C. Greene (historian) (1917–2008), American historian of science
- Joe Greene (Ontario politician) (John James Greene, 1920–1978), Canadian politician
- John Greene, abbot of Welbeck Abbey (1450)
See also
edit- John Green (disambiguation)
- Jack Greene (1930–2013), American country musician
- Jackie Greene (born 1980), American singer-songwriter and musician