KNB can refer to
- KNB EFX Group, an American special effects company
- Kanab Municipal Airport, an airport near Kanab, Utah
- Kitanihon Broadcasting, a Japanese media company
- National Security Committee of the Republic of Kazakhstan, also referred to as the NSC or KNB
- Kalaallit Nunaanni Brugseni, a Greenlandic supermarket chain better known as Brugseni