Kathleen Kennedy may refer to:
- Kathleen Cavendish, Marchioness of Hartington (1920–1948), born Kathleen Kennedy, sister of U.S. President John F. Kennedy
- Kathleen Kennedy Townsend (born 1951), Maryland politician and daughter of Robert F. Kennedy
- Kathleen Kennedy (producer) (born 1953), American film producer
- Kathleen "Kick" Kennedy (born 1988), philanthropist and daughter of Robert F. Kennedy Jr.