Keith Hughes may refer to:
- Keith Hughes (baseball) (born 1963), American outfielder for the New York Yankees
- Keith Hughes (basketball) (1968–2014), basketball player
- Keith Hughes (historian) (born 1972), American historian, educator, and host of HipHughes History
- Keith Hughes (rugby union) (born 1949), Welsh rugby union player
- Keith F. Hughes (1936–2021), American lawyer and politician
This disambiguation page lists articles about people with the same name.
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