Linoleate 9S-lipoxygenase (EC 1.13.11.58, 9-lipoxygenase, 9S-lipoxygenase, linoleate 9-lipoxygenase, LOX1 (gene), 9S-LOX) is an enzyme with systematic name linoleate:oxygen 9S-oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction
| Linoleate 9S-lipoxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.13.11.58 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- linoleate + O2 (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate
Linoleate 9S-lipoxygenase contains nonheme iron.
References
edit- ^ Vellosillo T, Martínez M, López MA, Vicente J, Cascón T, Dolan L, Hamberg M, Castresana C (March 2007). "Oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade". The Plant Cell. 19 (3): 831–46. doi:10.1105/tpc.106.046052. PMC 1867370. PMID 17369372.
- ^ Boeglin WE, Itoh A, Zheng Y, Coffa G, Howe GA, Brash AR (November 2008). "Investigation of substrate binding and product stereochemistry issues in two linoleate 9-lipoxygenases". Lipids. 43 (11): 979–87. doi:10.1007/s11745-008-3230-1. PMC 4710486. PMID 18795358.
- ^ Andreou AZ, Hornung E, Kunze S, Rosahl S, Feussner I (March 2009). "On the substrate binding of linoleate 9-lipoxygenases". Lipids. 44 (3): 207–15. doi:10.1007/s11745-008-3264-4. PMID 19037675. S2CID 4004916.
- ^ Bannenberg G, Martínez M, Hamberg M, Castresana C (February 2009). "Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana". Lipids. 44 (2): 85–95. doi:10.1007/s11745-008-3245-7. PMID 18949503. S2CID 19170797.
External links
edit- Linoleate+9S-lipoxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
