Wikipedia

Plum Island Animal Disease Center

(Redirected from Lab 257)
For Plum Island, see Plum Island (New York).

Plum Island Animal Disease Center (PIADC) is a United States federal research facility dedicated to the study of foreign animal diseases of livestock. It is a national laboratory of the Department of Homeland Security (DHS) Directorate for Science and Technology (S&T), and operates as a partnership with the U.S. Department of Agriculture (USDA).[1] The facility's director is Larry Barrett.[2]

Plum Island Animal Disease Center
PIADC logo
Buildings 100 and 101 at the Plum Island Animal Disease Center
Established1954
Budget$16.5 million
Field of research
Foreign animal diseases
DirectorLarry Barrett
LocationPlum Island, New York, U.S.
41°10′44″N 72°12′20″W / 41.178889°N 72.205556°W / 41.178889; -72.205556
11957
Operating agency
United States Department of Homeland Security
WebsiteDHS site
Map
Plum Island Animal Disease Center is located in Long Island
Plum Island Animal Disease Center
Location in Long Island

Isolated on Plum Island off the eastern tip of Long Island, New York, the center has been tasked with protecting America's livestock from animal diseases since 1954. It is the only facility in the country authorized to work with live foot-and-mouth disease (FMD) samples, and specializes in the study of FMD and African swine fever.[3] At the height of the Cold War, study of biological weapons for use against livestock was conducted at the site, ending in 1969 when President Nixon declared an end to the United States' offensive bioweapons program. Today the facility maintains laboratories up to biosafety level 3, and has remained controversial as a result of its high-risk work and proximity to the New York metropolitan area.

The facility is slated for closure in 2024[citation needed], with work moving to the National Bio and Agro-Defense Facility under construction in Manhattan, Kansas.

Location

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See also: Plum Island (New York)

The center is located on Plum Island near the northeast coast of Long Island in New York state. During the Spanish–American War, the island was purchased by the government for the construction of Fort Terry, which was later deactivated after World War II and then reactivated in 1952 for the Army Chemical Corps. The center comprises 70 buildings (many of them dilapidated) on 840 acres (3.4 km2).[4][5] Plum Island has its own fire department, power plant, water treatment plant, and security.[4][5] Any wild mammal seen on the island is killed to prevent the possible transmission of foot-and-mouth disease.[4] However, as Plum Island was named an important bird area by the New York Audubon Society, it has attracted different birds. Plum Island has placed osprey nests and bluebird boxes throughout the island. As of 2008, new kestrel houses were planned to be added.[6]

History

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In response to disease outbreaks in Mexico and Canada in 1954, the US Army gave the island to the Agriculture Department to establish a research center dedicated to the study of foot-and-mouth disease in cattle.[4]

The island was opened to news media for the first time in 1992.[5] In 1995, the Department of Agriculture was issued a $111,000 fine for storing hazardous chemicals on the island.[5]

Local Long Island activists prevented the center from expanding to include diseases that affect humans in 2000, which would require a Biosafety Level 4 designation; in 2002, the US Congress again considered the plan.[4]

The Wall Street Journal reported in January 2002 that many scientists and government officials wanted the lab to close, believing that the threat of foot-and-mouth disease was so remote that the center did not merit its $16.5 million annual budget.[4] In 2002, the Plum Island Animal Disease Center was transferred from the United States Department of Agriculture to the United States Department of Homeland Security.[citation needed]

In 2003, a whistleblower who voiced concerns about safety at the facility was fired by the contractor he worked for. He had discussed his concerns with aides to Senator Hillary Clinton.[7] A National Labor Relations Board judge found that the contractor, North Fork Services, had discriminated against the whistleblower.[7]

In 2020, the Department of Homeland Security plan to put the island up for auction after the conclusion of laboratory activities in 2023 was blocked by Congress. As part of ongoing COVID-19 pandemic relief legislation, Senator Chuck Schumer of New York negotiated a provision in the CARES Act that protects the island from being sold. Environmentalists had opposed the sale of the island because of its extensive wildlife habitats. After the final draft of the legislation was announced, Schumer said “It would have been a grave mistake to sell and develop Plum Island's 840-acres of habitat, which is home to many endangered species, that's why preventing the unnecessary sale requirement was a top priority of these negotiations."[8]

Replacement facility

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See also: National Bio and Agro-Defense Facility
 
The NBAF on the campus of Kansas State University in Manhattan, Kansas (2020)

On September 11, 2005, DHS announced that the Plum Island Animal Disease Research Center will be replaced by a new federal facility. The location of the new high-security animal disease lab, called the National Bio and Agro-Defense Facility (NBAF), is being built in Manhattan, Kansas.[9][10]

The plan was controversial almost immediately when it was unveiled, following a cost assessment by DHS and prime contractor Booz Allen Hamilton in which the agency determined that the cost of maintaining or moving the facility would be comparable.[10]

Those conclusions, as well as claims about the safety of the facility proposed were called into question several times, first by a 2007 Government Accountability Office study, which stated that claims by DHS that the work on foot and mouth disease performed on Plum Island can be performed "as safely on the mainland" is "not supported" by evidence.[11]

In 2012, DHS completed a risk assessment of the Kansas site that called the proposed facility "safe and secure".[12] In response, a 2012 review of the risk assessment by the National Research Council called it "seriously flawed".[13]

Despite controversy, the new facility is nearing completion, and transfer of laboratory contents from Plum Island to NBAF is to be complete by 2023. The USDA has named former director of Canada's Centers for Animal Disease Alfonso Clavijo as the director of the new facility.[14]

Activities

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PIADC's mission can be grouped into three main categories: diagnosis, research, and education.[citation needed]

Since 1971, PIADC has been educating veterinarians in foreign animal diseases. The center hosts several Foreign Animal Disease Diagnostic schools each year to train federal and state veterinarians and laboratory diagnostic staff, military veterinarians and veterinary school faculty.[citation needed]

At PIADC, the U.S. Department of Homeland Security (DHS) and U.S. Department of Agriculture (USDA) work together; DHS' Targeted Advanced Development unit partners with USDA, academia and industry scientists to deliver vaccines and antivirals to the USDA for licensure and inclusion in the USDA National Veterinary Vaccine Stockpile.[citation needed]

USDA Agricultural Research Service (ARS) performs basic and applied research to better formulate countermeasures against foreign animal diseases, including strategies for prevention, control and recovery. ARS focuses on developing faster-acting vaccines and antivirals to be used during outbreaks to limit or stop transmission. Antivirals prevent infection while vaccine immunity develops. The principal diseases studied are foot-and-mouth disease, classical swine fever, and vesicular stomatitis virus.[citation needed]

USDA Animal and Plant Health Inspection Services (APHIS) operates the Foreign Animal Disease Diagnostic Laboratory, an internationally recognized[citation needed] facility performing diagnostic testing of samples collected from U.S. livestock. APHIS also tests animals and animal products being imported into the U.S. APHIS maintains the North American Foot-and-Mouth Disease Vaccine Bank at PIADC and hosts the Foreign Animal Disease Diagnosticians training program, offering several classes per year to train veterinarians to recognize foreign animal diseases.[citation needed]

Research on biological weapons at PIADC ceased when the United States Biological Warfare program was ended in 1969 by President Richard Nixon.[15]

Biological weapons research

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The original anti-animal biological weapons mission was "to establish and pursue a program of research and development of certain anti-animal (BW) agents".[16] By August 1954 animals occupied holding areas at Plum Island and research was ongoing within Building 257.[17] The USDA facility, known as the Plum Island Animal Disease Center, continued work on biological warfare research until the U.S. program was ended by Richard Nixon in 1969.[15] The bio-weapons research at Building 257 and Fort Terry was shrouded in aura of mystery and secrecy.[18][19] The existence of biological warfare experiments on Plum Island during the Cold War era was denied for decades by the U.S. government. In 1993 Newsday unearthed documents proving otherwise and in 1994, Russian scientists inspected the Plum Island research facility to verify that these experiments had indeed ended.[19]

Diseases studied and outbreaks

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As a diagnostic facility, PIADC scientists study more than 40 foreign animal diseases, including classical swine fever and African swine fever.[4][10] PIADC runs about 30,000 diagnostic tests each year. PIADC operates Biosafety Level 3 Agriculture (BSL-3Ag), BSL-3 and BSL-2 laboratory facilities. The facility's research program includes developing diagnostic tools and biologicals for foot-and-mouth disease and other diseases of livestock.[4]

Because federal law stipulates that live foot-and-mouth disease virus cannot be studied on the mainland, PIADC is unique in that it is currently the only laboratory in the U.S. equipped with research facilities that permit the study of foot-and-mouth disease.[20]

Foot-and-mouth disease is extremely contagious among cloven-hooved animals, and people who have come in contact with it can carry it to animals.[7] Accidental outbreaks of the virus have caused catastrophic livestock and economic losses in many countries throughout the world.

Foot-and-mouth disease was eradicated from the U.S. in 1929 (with the exception of the stocks within the Plum Island center)[4] but is currently endemic to many parts of the world.

In 2012, two researchers at the facility, John Neilan and Michael Puckette, developed the first Foot-and-mouth disease vaccine which does not require live virus cultures in the manufacturing process, allowing vaccine development to occur safely and legally on U.S. mainland for the first time.[21]

Laboratory accidents

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Plum Island has experienced outbreaks of its own, including one in 1978 in which foot-and-mouth disease was released to animals outside the center, and two incidents in 2004 in which the disease was released within the center.[7][10]

In response to the two 2004 incidents, New York Senator Hillary Clinton and Congressman Tim Bishop wrote a letter to the Department of Homeland Security regarding their concerns about the center's safety: "We urge you to immediately investigate these alarming breaches at the highest levels, and to keep us apprised of all developments."[7]

Historic buildings

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Building 257

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Building No. 257 at Fort Terry, on Plum Island near Long Island, New York, was completed around 1911.[22] The original purpose of the building was to store weapons, such as mines, and the structure was designated the Combined Torpedo Storehouse and Cable Tanks building.[22] Fort Terry went through a period of activations and deactivations through World War II until the U.S. Army Chemical Corps took over the facility in 1952 for use in anti-animal biological warfare (BW) research.[15] The Chemical Corps planned a laboratory for the fort, to be housed in Building 257.[22] The conversion of Fort Terry to a BW facility required the remodeling of Building 257 and other structures.[15]

As work neared completion on the lab and other facilities in the spring of 1954 the mission of Fort Terry changed.[23] Construction was completed on the facilities on May 26, 1954, but the post was transferred to the USDA before the military could utilize the new laboratory facilities.[22] Fort Terry was officially transferred to the USDA on July 1, 1954, at the time scientists from the Bureau of Animal Industry were already working in Building 257.[22] Construction on a new lab facility, known as Building 101, also began about this time but was not completed until September 1956.[22]

A modernization program in 1977 aimed to update both Building 257 and Building 101, but the program was canceled in 1979 because of construction contract irregularities.[22] Plum Island facilities were essentially unchanged until a new modernization began in 1990.[22] Two-thirds of the laboratory facilities inside Building 101 were renovated and operations in Building 257 were consolidated into Building 101.[22] According to a United States Department of Homeland Security spokesperson in 2004, Building 257 was closed in 1995 and poses no health hazard.[18]

Building 101

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The structure is a 164,000-square-foot (15,200 m2) T-shaped white building.[17] It is situated on Plum Island's northwest plateau on a 10-acre (40,000 m2) site where it is buttressed by a steep cliff which leads into the ocean.[17] To the south-west of the building's site is the old Plum Island Lighthouse.[17]

Construction on Plum Island's new laboratory Building 101 began around July 1, 1954, around the same time that the Army's anti-animal bio-warfare (BW) facilities at Fort Terry were transferred to the U.S. Department of Agriculture.[24] Following the transfer, the facilities on Plum Island became known as the Plum Island Animal Disease Center.[24] The USDA's $7.7. million[17] Building 101 laboratory facility was dedicated on September 26, 1956.[24] Prior to the building's opening the area around it was sprayed with chemicals to deter insect or animal life from approaching the facility.[17] Upon its opening a variety of tests using pathogens and vectors were conducted on animals in the building.[17] Research on biological weapons at PIADC did not cease until the entire program was canceled in 1969 by Richard Nixon.[15]

A modernization program in 1977 aimed to update both Building 101 and another laboratory, Building 257, but the program was canceled in 1979 because of construction contract irregularities.[24] PIADC facilities were essentially unchanged until a new modernization began in 1990.[24] Two-thirds of the laboratory facilities inside Building 101 were renovated and operations from Building 257 were consolidated into Building 101.[24] Building 257 was closed, and a major expansion, known as Building 100, was completed on Building 101 in 1995.[24] According to the Department of Homeland Security (DHS), Building 257 currently poses no health hazard.[18]

Controversy

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Conspiracy theories

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Prolific but unfounded conspiracy theories have alleged that Lyme disease, first documented in nearby Lyme, Connecticut, was a biological weapon that originated in the Plum Island laboratory.[25] A discredited 2004 book entitled Lab 257: The Disturbing Story of the Government's Secret Plum Island Germ Laboratory fueled the conspiracy theories.[18][26] Archived specimens show that Lyme disease was endemic well before the establishment of Plum Island laboratory.[25] Additionally, Lyme disease was never a topic of research at Plum Island, according to the US Department of Homeland Security and Department of Agriculture.[3][18]

On July 12, 2008, a creature dubbed the Montauk Monster washed ashore at Ditch Plains Beach near the business district of Montauk, New York. The creature, a quadruped of indeterminate size, was dead when discovered, and was assumed by some to have come from Plum Island as a result of the currents and proximity to the mainland. Palaeozoologist Darren Naish studied the photograph and concluded from visible dentition and the front paws that the creature may have been a raccoon.[27] This was also the opinion of Larry Penny, the East Hampton Natural Resources Director.[28]

Terrorism

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When American educated Pakistani neuroscientist Aafia Siddiqui, a suspected al-Qaeda member, was captured in Afghanistan in July 2008, she had in her handbag handwritten notes referring to a "mass casualty attack" that listed various U.S. locations, including the Plum Island Animal Disease Center.[29] In February 2010, she was convicted of assault with a deadly weapon and attempting to kill U.S. servicemembers and FBI agents who sought to interrogate her.

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  • Plum Island and PIADC are the subject of a murder mystery novel, Plum Island, by Nelson DeMille. DeMille has said, "How could anthrax not be studied there? Every animal has it." While addressing popular culture fears of a germ warfare lab at Plum Island, overall, the facility is presented as doing the job described by the Federal Government—research into animal diseases that would either devastate our national livestock or jump to humans and devastate us. The novel portrays the investigation into the murder of two Plum Island scientists. The motive, initially thought to be germs for terrorists or germs for a biotech company, is really the search for the lost treasure of Captain Kidd, who sailed the waters around Long Island prior to his capture. Kidd's treasure has never been found.
  • Plum Island is also referred to in the 1991 psychological thriller The Silence of the Lambs, when the character of Hannibal Lecter is offered a transfer to a different psychiatric institution, as well as the promise of annual week-long supervised furlough to Plum Island, in exchange for his assistance in helping the FBI locate the whereabouts of the missing daughter of a prominent US Senator. It is later revealed in the film that the offer is bogus in the first place, used only as a ruse to elicit Lecter's cooperation.
  • The Plum Island facility served as the inspiration for the Mount Dragon research facility in the 1996 techno-thriller Mount Dragon, written by Douglas Preston and Lincoln Child.
  • The testing facility at Plum Island is the subject of a novel, The Poison Plum, by author Les Roberts.[30]
  • Plum Island and the facility there figure prominently in the 2014 horror novel, The Montauk Monster, by Hunter Shea, in which a bizarre carcass found on a beach in 2008 is an early version of vicious creatures now terrifying the Montauk community.
  • The Plum Island facility is mentioned in the television show Emergence as the takeoff point for a flight that crashes in Southold, New York. In reality, this would be impossible, as there are no airstrips on Plum Island.

References

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  1. ^ "PIADC Fact Sheet" (PDF). Department of Homeland Security.
  2. ^ "Inside the mysterious Plum Island Animal Disease Center". NBC4 WCMH-TV. 2019-05-07. Retrieved 2021-02-09.
  3. ^ a b "Plum Island Animal Disease Center". Department of Homeland Security. 6 July 2009. Retrieved 10 August 2020.
  4. ^ a b c d e f g h i "Bioterrorism Fears Revive Waning Interest In Agricultural Disease Lab on Plum Island". The Wall Street Journal. 2002-01-08. Retrieved 2008-05-17.
  5. ^ a b c d Miller, Judith (1999-09-22). "Long Island Lab May Do Studies Of Bioterrorism". The New York Times. Retrieved 2008-05-18.
  6. ^ "About Plum Island Animal Disease Center". Department of Homeland Security. 2008-12-28. Archived from the original on 2008-08-01. Retrieved 2008-08-04.
  7. ^ a b c d e Rather, John (2004-08-22). "Plum Island Reports Disease Outbreak". The New York Times. Retrieved 2008-05-17.
  8. ^ Bonfiglio, Briana (2020-12-22). "Congress Blocks Sale of Plum Island in Covid-19 Relief Bill". LI Press. Retrieved 2021-02-09.
  9. ^ "DHS: DHS Issues Record of Decision on Proposed National Bio- and Agro-Defense Facility". Dhs.gov. Archived from the original on 2011-07-06. Retrieved 2011-08-10.
  10. ^ a b c d Muller, Madison (8 September 2023). "A Mysterious Lab Is Shutting Down. It's the End of an Era for Biosecurity". Bloomberg News. Retrieved 20 September 2023.
  11. ^ "Study spurs request to not phase out Plum Island". Newsday.com. 2009-07-31. Retrieved 2011-08-10.
  12. ^ "DHS Issues Updated Site-Specific Risk Assessment For Proposed National Bio And Agro-Defense Facility (NBAF)". dhs.gov. 2 March 2012.
  13. ^ "Officials press feds for NBAF". LJWorld.com.
  14. ^ Avant, Sandra (October 1, 2019). "Alfonso Clavijo Named Director Of USDA National Bio And Agrio-Defense Facility : USDA ARS". USDA. Retrieved 20 September 2023.
  15. ^ a b c d e Cella, Alexandra. "An Overview of Plum Island: History, Research and Effects on Long Island", Long Island Historical Journal, Fall 2003/Spring 2004, Vol. 16, Nos. 1 and 2, pp. 176–181 (194–199 in PDF), accessed January 10, 2009.
  16. ^ Wheelis, Mark, et al. Deadly Cultures: Biological Weapons Since 1945, (Google Books), Harvard University Press, 2006 pp. 225–228, (ISBN 0674016998).
  17. ^ a b c d e f g Carroll, Michael C. Lab 257: The Disturbing Story of the Government's Secret Plum Island Germ Laboratory, (Google Books), HarperCollins, 2004, pp. 45–48, 60, (ISBN 0060011416).
  18. ^ a b c d e Dunn, Adam. "The mysterious lab off New York's shore", CNN.com, April 2, 2004, accessed January 10, 2009.
  19. ^ a b Lambert, Bruce. "Closely Guarded Secrets: Some Islands You Can't Get to Visit", The New York Times, May 17, 1998, accessed January 10, 2009.
  20. ^ U.S. General Accounting Office. "High-Containment Biosafety Laboratories: DHS Lacks Evidence to Conclude That Foot-and-Mouth Disease Research Can Be Done Safely on the U.S. Mainland". GAO-08-821T. 22 May 2008. p. 1.
  21. ^ "Snapshot: New Patent-Pending Process for FMD Vaccine". Department of Homeland Security. 2020-06-10. Retrieved 2021-02-09.
  22. ^ a b c d e f g h i "1669–2003: A Partial History of Plum Island Archived 2009-03-09 at the Wayback Machine", United States Animal Health Association Newsletter, Vol. 30, No. 4, October 2003, pp. 5, 26, accessed January 10, 2009.
  23. ^ Carroll, Michael C. Lab 257: The Disturbing Story of the Government's Secret Plum Island Germ Laboratory, (Google Books), HarperCollins, 2004, pp. 45–48, (ISBN 0060011416).
  24. ^ a b c d e f g "1669–2003: A Partial History of Plum Island Archived 2009-03-09 at the Wayback Machine", United States Animal Health Association Newsletter, Vol. 30, No. 4, October 2003, pp. 5, 26, accessed January 10, 2009.
  25. ^ a b Telford, Sam (11 August 2019). "No, Lyme disease is not an escaped military bioweapon, despite what conspiracy theorists say". Washington Post. Retrieved 10 August 2020.
  26. ^ Kirby, Reid. "Book Reviews Archived 2009-03-09 at the Wayback Machine", Army Chemical Review, January–June 2005, accessed January 10, 2009.
  27. ^ "What was the Montauk monster? : Tetrapod Zoology". Scienceblogs.com. 2008-08-04. Archived from the original on 2012-05-07. Retrieved 2009-07-14.
  28. ^ "The Hound of Bonacville". Indyeastend.com – The Independent. July 23, 2008. Archived from the original on July 22, 2012. Retrieved June 8, 2009.
  29. ^ Weiser, Benjamin (September 2, 2008). "Indictment Hints of Plan to Attack Landmarks". The New York Times. Retrieved April 25, 2015.
  30. ^ Roberts, Les. The Poison Plum. Les Roberts. Archived from the original on 2007-12-13.

Further reading

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  • The Plum Island Animal Disease Laboratory (1956)
  • U.S. General Accounting Office. (2003). Combating bioterrorism: actions needed to improve security at Plum Island Animal Disease Center. Washington, D.C.: Author.
  • U.S. Government Accountability Office. (2005). Plum Island Animal Disease Center: DHS and USDA are successfully coordinating current work, but long-term plans are being assessed: report to congressional committees. Washington, D.C.: Author.
  • U.S. Government Accountability Office. (2007). Plum Island Animal Disease Center: DHS has made significant progress implementing security recommendations, but several recommendations remain open. Washington, D.C.: Author.
  • U.S. Government Accountability Office. (2008). High-containment biosafety laboratories: DHS lacks evidence to conclude that foot-and-mouth disease research can be done safely on the U.S. mainland: testimony before the Subcommittee on Oversight and Investigations, Committee on Energy and Commerce, House of Representatives. Washington, D.C.: Author.
  • U.S. Government Accountability Office. (2009). Biological research: observations on DHS's analyses concerning whether FMD research can be done as safely on the mainland as on Plum Island: report to congressional committees. Washington, D.C.: Author.
  • U.S. House of Representatives. (2008). Germs, viruses, and secrets: government plans to move exotic disease research to the mainland United States: hearing before the Subcommittee on Oversight and Investigations of the Committee on Energy and Commerce, House of Representatives, one hundred tenth congress, second session, May 22, 2008. Washington, D.C.: Government Printing Office.
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