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Estradiol valerate/dienogest (EV/DNG), sold under the brand names Lafamme, Natazia and Qlaira among others, is a combination product of estradiol valerate, an estrogen, and dienogest, a progestogen, which is used in menopausal hormone therapy in and as a birth control pill to prevent pregnancy in women. It is taken by mouth.
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| Combination of | |
|---|---|
| Estradiol valerate | Estrogen |
| Dienogest | Progestogen |
| Clinical data | |
| Trade names | Lafamme, Natazia, Qlaira |
| Other names | EV/DNG; SH T00658ID; Bay 86-5027; BAY86-5027 |
| AHFS/Drugs.com | Professional Drug Facts |
| MedlinePlus | a601050 |
| License data | |
| Pregnancy category | |
| Routes of administration | By mouth |
| Drug class | Estrogen; Progestogen |
| ATC code | |
| Legal status | |
| Legal status |
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| Identifiers | |
| CAS Number | |
| PubChem CID | |
| KEGG | |
Birth control pills containing EV/DNG are associated with a significantly increased risk of venous thromboembolism.[2] However, they are associated with a significantly lower risk of venous thromboembolism than birth control pills containing ethinylestradiol and a progestin.[2]
See also
editReferences
edit- ^ a b c "Dienogest / estradiol (Natazia) Use During Pregnancy". Drugs.com. 27 January 2020. Retrieved 18 March 2020.
- ^ a b Fruzzetti F, Cagnacci A (2018). "Venous thrombosis and hormonal contraception: what's new with estradiol-based hormonal contraceptives?". Open Access J Contracept. 9: 75–79. doi:10.2147/OAJC.S179673. PMC 6239102. PMID 30519125.
External links
edit- "Dienogest mixture with Estradiol valerate". Drug Information Portal. U.S. National Library of Medicine.
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