List of cigarette smoke carcinogens
(Redirected from List of cigarette smoke constituents)
Commercial tobacco smoke is a mixture of more than 5,000 chemicals.[1] A 2011 report in the International Journal of Environmental Research and Public Health (IJERPH) lists 65 carcinogens or possible carcinogens: "Our list of hazardous smoke components includes all nine components reported in mainstream cigarette smoke that are known human carcinogens (IARC Group I carcinogens), as well as all nine components that are probably carcinogenic to humans (IARC Group 2A carcinogens). In addition, it contains 34 of the 48 components that are possibly carcinogenic to humans (IARC Group 2B carcinogens)."[1]
IJERPH table
edit- "1Cancer inhalation risk values provide an excess lifetime exposure risk, in this case the human lung cancer risk at a 1 in 100,000 (E-5) level."
| Smoke component | Cancer risk value1 | Institute |
|---|---|---|
| 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) | 1.0E-04 | U.S. EPA |
| 1,1-Dimethylhydrazine | 2.0E-06 | ORNL |
| 1,3-Butadiene | 3E-04 | U.S. EPA |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TEQ) | 2.6E-04 | Cal EPA |
| 2-Amino-3-methyl-9H-pyrido[2,3-b]indole (MeAaC) | 2.9E-05 | Cal EPA |
| 2-Amino-3-methylimidazo[4,5-b]quinoline (IQ) | 2.5E-05 | Cal EPA |
| 2-Amino-6-methyl[1,2-a:3',2"-d]imidazole (GLu-P-1) | 7.1E-06 | Cal EPA |
| 2-Aminodipyrido[1,2-a:3',2"-d]imidazole (GLu-P-2) | 2.5E-05 | Cal EPA |
| 2-Aminonaphthalene | 2.0E-05 | Cal EPA |
| 2-Nitropropane | Cal EPA | |
| 2-Toluidine | 2.0E-04 | Cal EPA |
| 3-Amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) | 1.4E-06 | Cal EPA |
| 3-Amino-1-methyl-5H-pyrido[4,3-b]-indole (Trp-P-2) | 1.1E-05 | Cal EPA |
| 4-Aminobiphenyl | 1.7E-06 | Cal EPA |
| 5-Methylchrysene | 9.1E-06 | Cal EPA |
| 7H-Dibenzo(c,g)carbazole | 9.1E-06 | Cal EPA |
| 2-Amino-9H-pyrido[2,3-b]indole (AaC) | 8.8E-05 | Cal EPA |
| Acetaldehyde | 4.5E-03 | U.S. EPA |
| Acetamide | 5.0E-04 | Cal EPA |
| Acrylamide | 8E-3 | |
| Acrylonitrile | 1.5E-04 | U.S. EPA |
| Aniline | B2—probable human carcinogen | U.S. EPA |
| Arsenic | 2.3E-06 | U.S. EPA |
| Benz[a]anthracene | 9.1E-05 | Cal EPA |
| Benzene | 1.3E-03 | U.S. EPA |
| Benzo[a]pyrene | 9.1E-06 | Cal EPA |
| Benzo[j]fluoranthene | 9.1E-05 | Cal EPA |
| Beryllium | 4.2E-06 | |
| Cadmium | 5.6E-06 | U.S. EPA |
| Carbazole | 1.8E-03 | NATA |
| Chloroform, | 4.3E-04 | U.S. EPA |
| Chromium VI | 8.3E-07 | U.S. EPA |
| Chrysene | 9.1E-04 | Cal EPA |
| Di(2-ethylhexyl) phthalate | 4.2E-03 | Cal EPA |
| Dibenzo[a,i]pyrene | 9.1E-07 | Cal EPA |
| Dibenzo[a,h]acridine | 9.1E-05 | Cal EPA |
| Dibenzo[a,h]anthracene | 8.3E-06 | Cal EPA |
| Dibenzo[a,j]acridine | 9.1E-05 | Cal EPA |
| Dibenzo[a,h]pyrene | 9.1E-07 | Cal EPA |
| Dibenzo[a,l)pyrene | 9.1E-07 | Cal EPA |
| Dibenzo[a,e]pyrene | 9.1E-06 | Cal EPA |
| Dibenzo[c,g]carbazole | 9.1E-06 | Cal EPA |
| Ethyl carbamate | 3.5E-05 | Cal EPA |
| Ethylene oxide | 1.1E-04 | Cal EPA |
| Ethylenethiourea | 7.7E-04 | Cal EPA |
| Formaldehyde | 7.7E-04 | U.S. EPA |
| Hydrazine | 2.0E-06 | U.S. EPA |
| Indeno(1,2,3-c,d)pyrene | 9.1E-05 | Cal EPA |
| Lead | 8.3E-04 | Cal EPA |
| N-nitrosodi-n-butylamine (NBUA) | 6.3E-06 | U.S. EPA |
| N-nitrosodimethylamine (NDMA) | 7.1E-07 | U.S. EPA |
| N-nitrosodiethanolamine | 1.3E-05 | Cal EPA |
| N-nitrosodiethylamine | 2.3E-07 | U.S. EPA |
| N-nitrosoethylmethylamine | 1.6E-06 | Cal EPA |
| N-Nitrosonornicotine (NNN) | 2.5E-05 | Cal EPA |
| N-Nitroso-N-propylamine | 5.0E-06 | Cal EPA |
| N-nitrosopiperidine | 3.7E-06 | Cal EPA |
| N-nitrosopyrrolidine | 1.6E-05 | U.S. EPA |
| o-Cresol | C- possible human carcinogen | U.S. EPA |
| p-Benzoquinone | C- possible human carcinogen | U.S. EPA |
| p-Cresol | C- possible human carcinogen | U.S. EPA |
| Polonium-210 | 925.9 | ORNL3 |
| Propylene oxide | 2.7E-03 | U.S. EPA |
| Trichloroethylene | 82 | HC |
| Vinyl chloride | 1.1E-03 | U.S. EPA |
See also
editReferences
edit- ^ a b c Talhout, Reinskje; Schulz, Thomas; Florek, Ewa; van Benthem, Jan; Wester, Piet; Opperhuizen, Antoon (February 2011). "Hazardous Compounds in Tobacco Smoke". International Journal of Environmental Research and Public Health. 8 (2): 613–628. doi:10.3390/ijerph8020613. ISSN 1661-7827. PMC 3084482. PMID 21556207. See Table 1.