Lonely Road may refer to:
- Lonely Road (The Red Jumpsuit Apparatus album), or the title song
- Lonely Road (Denny Laine album), or the title song
- "Lonely Road" (song), by Machine Gun Kelly and Jelly Roll
- "Lonely Road", a song by Paul McCartney from Driving Rain
- The Lonely Road, album by jazz guitarist David Becker
- The Lonely Road (1923 film), an American drama
- Lonely Road (novel), a novel by Nevil Shute
- Lonely Road (film), a 1936 British drama based on Shute's novel
- Lonely Road Books, an American small-press publisher