Clotrimazole/betamethasone dipropionate, sold under the brand name Lotrisone among others, is a topical medication used for the treatment of fungal infections of the feet, groin, and body in people 17 years of age and older.[1][2] It is a combination of clotrimazole and betamethasone dipropionate.[1] It is applied to the skin.[1]
| Combination of | |
|---|---|
| Clotrimazole | Azole antifungal |
| Betamethasone dipropionate | Corticosteroid |
| Clinical data | |
| Trade names | Lotrisone |
| AHFS/Drugs.com | Monograph |
| License data | |
| Routes of administration | Topical |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| KEGG | |
Common side effects include paresthesia, rash, edema, and secondary infections.[1]
In 2021, it was the 274th most commonly prescribed medication in the United States, with more than 900,000 prescriptions.[3][4]
Medical uses
editClotrimazole/betamethasone dipropionate is indicated for the topical treatment of symptomatic inflammatory tinea pedis, tinea cruris, and tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum in people 17 years of age and older.[1]
Society and culture
editLegal status
editClotrimazole/betamethasone dipropionate cream was approved for medical use in the United States in July 1984,[5] and the lotion was approved for use in the United States in December 2000.[6]
References
edit- ^ a b c d e f "Lotrisone- clotrimazole and betamethasone dipropionate cream". DailyMed. 14 June 2019. Archived from the original on 28 August 2021. Retrieved 13 April 2020.
- ^ Greenberg HL, Shwayder TA, Bieszk N, Fivenson DP (2002). "Clotrimazole/betamethasone diproprionate: a review of costs and complications in the treatment of common cutaneous fungal infections". Pediatric Dermatology. 19 (1): 78–81. doi:10.1046/j.1525-1470.2002.00027.x. PMID 11860579. S2CID 23472426.
- ^ "The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
- ^ "Betamethasone; Clotrimazole - Drug Usage Statistics". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
- ^ "Lotrisone: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Archived from the original on 1 October 2020. Retrieved 13 April 2020.
- ^ "Drug Approval Package: Lotrisone (Clotrizazole & Betamethasone Dipropionate) NDA #020010". U.S. Food and Drug Administration (FDA). 8 September 2004. Archived from the original on 7 April 2021. Retrieved 13 April 2020.
External links
edit- "Betamethasone Topical: MedlinePlus Drug Information". MedlinePlus.
- "Clotrimazole Topical: MedlinePlus Drug Information". MedlinePlus.
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