Mitochondrial methionyl-tRNA formyltransferase is a protein that in humans is encoded by the MTFMT gene .[ 5]
The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA.[ 5] Recessive-type mutations in MTFMT have been shown to cause mitochondrial disease .[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000103707 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000059183 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ a b "Entrez Gene: Mitochondrial methionyl-tRNA formyltransferase" . Retrieved 2011-09-20 .
^ Tucker EJ, Hershman SG, Köhrer C, Belcher-Timme CA, Patel J, Goldberger OA, et al. (September 2011). "Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation" . Cell Metabolism . 14 (3): 428–434. doi :10.1016/j.cmet.2011.07.010 . PMC 3486727 . PMID 21907147 .