Hydrocortamate

Hydrocortamate
Clinical data
Trade names	Magnacort, Ulcort
Other names	11β,17α-Dihydroxy-3,20-dioxopregn-4-en-21-yl N,N-diethylglycinate
Routes of; administration	Topical
Pharmacokinetic data
Excretion	Hepatic
Identifiers
	IUPAC name [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15, 16-decahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] 2-(diethylamino)acetate;
CAS Number	76-47-1;
PubChem CID	408334;
PubChem SID	46509076;
DrugBank	DB00769;
ChemSpider	361312;
UNII	Y3N00BK5WK;
ChEBI	CHEBI:50851;
ChEMBL	ChEMBL1201263;
CompTox Dashboard (EPA)	DTXSID1057824 ;
ECHA InfoCard	100.000.877
Chemical and physical data
Formula	C27H41NO6
Molar mass	475.626 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)COC(=O)CN(CC)CC;
	InChI InChI=1S/C27H41NO6/c1-5-28(6-2)15-23(32)34-16-22(31)27(33)12-10-20-19-8- 7-17-13-18(29)9-11-25(17,3)24(19)21(30)14-26(20,27)4/h13,19-21,24,30, 33H,5-12,14-16H2,1-4H3; Key:FWFVLWGEFDIZMJ-UHFFFAOYSA-N;

Hydrocortamate (brand names Magnacort, Ulcortis) is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties.^[1]^[2] It is used topically to treat inflammation due to corticosteroid-responsive dermatoses.^[3]

References