Margaret Williams may refer to:
- Margaret Lindsay Williams (1888–1960), Welsh artist
- Maggie Williams (born 1954), American campaign manager for Hillary Clinton
- Peggy R. Williams, American college president
- Margaret Vyner (1914–1993), actress and playwright
- Maisie Williams (born 1997 as Margaret Williams), British actress
- Margaret Williams (film director) (1950–2024), British film and television director