Maria de la Cruz may refer to:
- María de la Cruz (1912–1995), Chilean activist
- Juan dela Cruz, national personification of the Philippines in the feminized form
- María de la Cruz Castro Ricalde, Mexican writer, professor and researcher
- Maria dela Cruz (born 1993), Filipino-American soccer player
- María Victoria de la Cruz (1916–1999), Cuban-Mexican cardiologist and embryologist
This disambiguation page lists articles associated with the title Maria de la Cruz.
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