Mesovouni (Greek: Μεσοβούνι) may refer to several places in Greece:
- Mesovouni, Ioannina , a village in the municipal unit Central Zagori, Ioannina regional unit
- Mesovouni, Karditsa, a village in the municipal unit Argithea, Karditsa regional unit
- Mesovouni, Thesprotia , a village in the municipal unit Margariti, Thesprotia