Monometacrine

Monometacrine
Clinical data
Other names	Desmethyldimetacrine; Nordimetacrine; N-Desmethyldimetacrine; SD-735; NSC-100296
Identifiers
	IUPAC name 3-(9,9-dimethylacridin-10-yl)-N-methylpropan-1-amine;
CAS Number	4757-49-7;
PubChem CID	145765;
ChemSpider	128589;
UNII	3FDC82890Y;
ChEMBL	ChEMBL2104752;
CompTox Dashboard (EPA)	DTXSID40197201 ;
Chemical and physical data
Formula	C19H24N2
Molar mass	280.415 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC1(C2=CC=CC=C2N(C3=CC=CC=C31)CCCNC)C;
	InChI InChI=1S/C19H24N2/c1-19(2)15-9-4-6-11-17(15)21(14-8-13-20-3)18-12-7-5-10-16(18)19/h4-7,9-12,20H,8,13-14H2,1-3H3; Key:PGSOFANFWNSSRA-UHFFFAOYSA-N;

Monometacrine (INNTooltip International Nonproprietary Name; developmental code name SD-735), also known as desmethyldimetacrine, is a drug of the tricyclic family described as an antidepressant which was never marketed.^[1]^[2]^[3] It was first described in the literature by 1966.^[1] The drug is the N-desmethyl analogue of dimetacrine and is a metabolite of dimetacrine.^[1]^[3]

References

^ ^a ^b ^c Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 835. ISBN 978-1-4757-2085-3. Retrieved 20 October 2024.
^ Negwer M, Scharnow HG (2001). Organic-chemical Drugs and Their Synonyms: An International Survey. Wiley-VCH. p. 1788. ISBN 978-3-527-30247-5. Retrieved 20 October 2024.
^ ^a ^b "Monometacrine". Inxight Drugs. National Center for Advancing Translational Sciences (NCATS). Retrieved 20 October 2024.

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[Elks2014-1] Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 835. ISBN 978-1-4757-2085-3. Retrieved 20 October 2024.

[NegwerScharnow2001-2] Negwer M, Scharnow HG (2001). Organic-chemical Drugs and Their Synonyms: An International Survey. Wiley-VCH. p. 1788. ISBN 978-3-527-30247-5. Retrieved 20 October 2024.

[InxightDrugs-3] "Monometacrine". Inxight Drugs. National Center for Advancing Translational Sciences (NCATS). Retrieved 20 October 2024.

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