1-Tetradecanol, or commonly myristyl alcohol (from Myristica fragrans – the nutmeg plant), is a straight-chain saturated fatty alcohol, with the molecular formula CH3(CH2)12CH2OH. It is a white waxy solid that is practically insoluble in water, soluble in diethyl ether, and slightly soluble in ethanol.[2]
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| Names | |
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| Preferred IUPAC name
Tetradecan-1-ol | |
| Other names
Myristyl alcohol
Tetradecyl alcohol | |
| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.003.637 |
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| KEGG | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C14H30O | |
| Molar mass | 214.393 g·mol−1 |
| Density | 0.824 g/cm3 |
| Melting point | 38 °C (100 °F; 311 K) |
| Boiling point | >260 °C |
| Hazards | |
| GHS labelling: | |
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| Warning | |
| H410 | |
| P273, P391, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Production
edit1-Tetradecanol may be prepared by the hydrogenation of myristic acid (or its esters); myristic acid itself can be found in nutmeg (from where it gains its name) but is also present in palm kernel oil and coconut oil and it is from these that the majority of 1-tetradecanol is produced.[3] It may also be produced from petrochemical feedstocks via either the Ziegler process.
Uses
editAs with other fatty alcohols, 1-tetradecanol is used as an ingredient in cosmetics such as cold creams for its emollient properties. It is also used as an intermediate in the chemical synthesis of other products such as surfactants.
Toxicity
editLike other fatty alcohols, myristyl alcohol has very low acute toxicity, with LD50 >5000 mg/kg (oral, rat).[2]
References
edit- ^ Merck Index, 12th Edition, 6418.
- ^ a b Noweck, Klaus; Grafahrend, Wolfgang. "Fatty Alcohols". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a10_277.pub2. ISBN 978-3527306732.
- ^ Kreutzer, Udo R. (February 1984). "Manufacture of Fatty Alcohols Based on Natural Fats and Oils". Journal of the American Oil Chemists' Society. 61 (2): 343–348. doi:10.1007/BF02678792. S2CID 84849226.
External links
edit- "MSDS Number: ALCH414-1" (PDF). Procter and Gamble Chemicals. 2002-06-17. Archived from the original (PDF) on 2006-03-11. (MSDS for 1-tetradecanol / Myristyl Alcohol)