Potassium-dependent sodium-calcium exchanger

(Redirected from Na+/(Ca2+-K+) exchanger)

Potassium-dependent sodium-calcium exchanger also known as solute carrier family 24 (SLC24) is a type of sodium-calcium exchanger that requires potassium to function.[1]

Family members

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Human genes that encode members of the potassium-dependent sodium-calcium exchanger family include:

solute carrier family 24, member 1
Identifiers
SymbolSLC24A1
Alt. symbolsNCKX1
NCBI gene9187
HGNC10975
OMIM603617
RefSeqNM_004727
UniProtO60721
Other data
LocusChr. 15 q22
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solute carrier family 24, member 2
Identifiers
SymbolSLC24A2
Alt. symbolsNCKX2
NCBI gene25769
HGNC10976
OMIM609838
RefSeqNM_020344
UniProtQ9UI40
Other data
LocusChr. 9 p22-p13
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solute carrier family 24, member 3
Identifiers
SymbolSLC24A3
Alt. symbolsNCKX3
NCBI gene57419
HGNC10977
OMIM609839
RefSeqNM_020689
UniProtQ9HC58
Other data
LocusChr. 20 p13
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solute carrier family 24, member 4
Identifiers
SymbolSLC24A4
Alt. symbolsNCKX4
NCBI gene123041
HGNC10978
OMIM609840
RefSeqNM_153646
UniProtQ8NFF2
Other data
LocusChr. 14 q32
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solute carrier family 24, member 5
Identifiers
SymbolSLC24A5
Alt. symbolsNCKX5
NCBI gene283652
HGNC20611
OMIM609802
RefSeqNM_205850
UniProtQ71RS6
Other data
LocusChr. 15 q15.2
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solute carrier family 24, member 6
Identifiers
SymbolSLC24A6
Alt. symbolsNCKX6
NCBI gene80024
HGNC26175
OMIM609841
RefSeqNM_024959
UniProtQ6J4K2
Other data
LocusChr. 12 q24
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StructuresSwiss-model
DomainsInterPro

References

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  1. ^ Schnetkamp PP (February 2004). "The SLC24 Na+/Ca2+-K+ exchanger family: vision and beyond". Pflügers Archiv. 447 (5): 683–8. doi:10.1007/s00424-003-1069-0. PMID 14770312. S2CID 37553960.
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