Wikipedia

Nepovirus

(Redirected from Nepoviruses)
Not to be confused with Nipah virus.

Nepovirus is a genus of viruses in the order Picornavirales, in the family Secoviridae, in the subfamily Comovirinae. Plants serve as natural hosts. There are 40 species in this genus.[1][2] Nepoviruses, unlike the other two genera (Comovirus and Fabavirus) in the subfamily Comovirinae, are transmitted by nematodes.[3]

Nepovirus
Crystal structure of Grapevine Fanleaf Virus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Picornavirales
Family: Secoviridae
Subfamily: Comovirinae
Genus: Nepovirus
Species

see text

Taxonomy

edit

The genus contains the following species:[2]

Structure

edit

Viruses in Nepovirus are non-enveloped, with icosahedral geometries, and T=pseudo3 symmetry. The diameter is around 28-30 nm. Genomes are linear and segmented, bipartite, around 23.9kb in length.[1]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Nepovirus Icosahedral Pseudo T=3 Non-enveloped Linear Segmented

Life cycle

edit

Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. The virus exits the host cell by tubule-guided viral movement. Plants serve as the natural host. The virus is transmitted via a vector (nematodes, mite, and thrips). Transmission routes are vector.[1]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Nepovirus Plants None Viral movement; mechanical inoculation Viral movement Cytoplasm Cytoplasm Nematodes; mites; thrips

Genome

edit

Nepoviruses are classified as type IV viruses under the Baltimore classification system, and consequently contain bipartite, linear, single stranded positive sense RNA genomes. The two genome segments are encapsulated separately into two different icosahedral particles. Each of the genome segments produces a different polypeptide, which undergoes a series of steps (i.e. proteolysis, and other post-translational modifications) in order to produce a functional protein.[3]

RNA1

edit

The first segment (RNA1) is approximately 8,000 nucleotides in length and appears as a single copy in each B type virion. It encodes the proteins that are important in replication and is the first gene to be activated.[3]

RNA2

edit

The second segment (RNA2) is approximately 4,000–7,000 nucleotides in length and usually appears as a single copy in each M type virion. It encodes the proteins that are important in cell-cell transmission and evasion of cellular defenses.[3]

References

edit
  1. ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 21 May 2021.
  3. ^ a b c d "Notes on Genus: Nepovirus". Retrieved 6 August 2007.
edit
Retrieved from "https://en.wikipedia.org/w/index.php?title=Nepovirus&oldid=1136465291"