Nespelem may also refer to:
- Nespelem, Washington, a city in eastern Washington state.
- Nespelem River, a tributary of the Columbia River.
- Nespelem (tribe), a Native American tribe
- Nespelem (art), an art movement and colony located in the Nespelem, Washington area
- Nespelem, a stern-wheel steamboat later named the Robert Young.
This disambiguation page lists articles associated with the title Nespelem.
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