Mucinous nevus is a rare cutaneous condition characterized by hamartoma that can be congenital or acquired.[1] Mucinous nevus presents as multiple skin-coloured or brown asymptomatic papules or plaques. Mucinous nevus is diagnosed based of histological features. Treatment is not needed.
| Mucinous nevus | |
|---|---|
| Other names | Nevus mucinosus |
| Specialty | Dermatology |
Signs and symptoms
editMucinous nevus appears as several skin-coloured to brownish papules or plaques that are asymptomatic; the individual lesions merge and expand to form a unilateral or zosteriform feature that is verrucous or nevoid.[2][3] It normally starts to develop in early adulthood or from birth.[4] The main location is the trunk, which includes the back.[2][5]
Causes
editThere has been reports of familial mucinous nevus, however there have been no reports of genetic abnormalities.[5][4]
Diagnosis
editHistologically, diffuse band-like mucin deposits in the uppermost layer of the dermis are indicative of mucinous nevus.[6] Hyaluronic acid is assumed to be the component of mucin since it reacts positively with alcian blue at pH 2.5 but does not at pH 0.5.[7][8]
Treatment
editMucinous nevi are benign and don't need to be treated other than for aesthetic reasons.[2] Carbon dioxide laser therapy, scalpel dermabrasion, and surgical excision are treatment options.[9]
See also
editReferences
edit- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
- ^ a b c Cobos, Gabriela; Braunstein, Inbal; Abuabara, Katrina; Chu, Emily Y.; James, William (2014-09-01). "Mucinous Nevus: Report of a Case and Review of the Literature". JAMA Dermatology. 150 (9): 1018. doi:10.1001/jamadermatol.2013.9451. ISSN 2168-6068. PMID 25029469.
- ^ Tardío, Juan C.; Granados, Rosario (2010-07-08). "The cellular component of the mucinous nevus consists of CD34-positive fibroblasts". Journal of Cutaneous Pathology. 37 (9). Wiley: 1019–1020. doi:10.1111/j.1600-0560.2009.01426.x. ISSN 0303-6987. PMID 19765172.
- ^ a b CHEN, CHIA-WEI; TSAI, TSEN-FANG; CHEN, YU-FU; HUNG, CHIH-MING (2008). "Familial Mucinous Nevus". Pediatric Dermatology. 25 (2). Wiley: 288–289. doi:10.1111/j.1525-1470.2008.00664.x. ISSN 0736-8046. PMID 18429813.
- ^ a b Perez-Crespo, M; Lopez-Navarro, N; Betlloch, I; Herrera, E; Niveiro, M; Gallego, E (2011-09-25). "Acquired and familial mucinous nevus". International Journal of Dermatology. 50 (10). Wiley: 1283–1285. doi:10.1111/j.1365-4632.2010.04520.x. ISSN 0011-9059. PMID 21950298.
- ^ Lee, Min Young; Byun, Ji Yeon; Choi, Hae Young; Choi, You Won (2018). "Mucinous Nevus". Annals of Dermatology. 30 (4). Korean Dermatological Association and The Korean Society for Investigative Dermatology: 465–467. doi:10.5021/ad.2018.30.4.465. ISSN 1013-9087. PMC 6029955. PMID 30065589.
- ^ Lim, J-H.; Cho, S-H.; Kim, H-O.; Kim, C-W.; Park, Y-M. (2003). "Mucinous naevus with atypical features". British Journal of Dermatology. 148 (5). Oxford University Press (OUP): 1064–1066. doi:10.1046/j.1365-2133.2003.05334.x. ISSN 0007-0963. PMID 12786849.
- ^ BRAKMAN, M.; STARINK, TH.M.; TAFELKRUYER, J.; BOS, J.D. (1994). "Linear connective tissue naevus of the proteoglycan type ('naevus mucinosus')". British Journal of Dermatology. 131 (3). Oxford University Press (OUP): 368–370. doi:10.1111/j.1365-2133.1994.tb08526.x. ISSN 0007-0963.
- ^ Chi, Ching-Chi; Wang, Shu-Hui; Lin, Paul Y. (2009). "Combined epidermal-connective tissue nevus of proteoglycan (a type of mucinous nevus): a case report and literature review". Journal of Cutaneous Pathology. 36 (7). Wiley: 808–811. doi:10.1111/j.1600-0560.2008.01123.x. ISSN 0303-6987. PMID 19519615.
Further reading
edit- Song, Byong Han; Park, Saebomi; Park, Eun Joo; Kwon, In Ho; Kim, Kwang Ho; Kim, Kwang Joong (2012). "Mucinous Nevus With Fat". The American Journal of Dermatopathology. 34 (8). Ovid Technologies (Wolters Kluwer Health): e146–e148. doi:10.1097/dad.0b013e31825a8b46. ISSN 0193-1091. PMID 22878365.
- Kim, Eun Jee; Jo, Seong-Jin; Cho, Kwang Hyun (2014). "A Case of Mucinous Nevus Clinically Mimicking Nevus Lipomatosus Superficialis". Annals of Dermatology. 26 (4). Korean Dermatological Association and The Korean Society for Investigative Dermatology: 549–550. doi:10.5021/ad.2014.26.4.549. ISSN 1013-9087. PMC 4135125. PMID 25143699.