OFD may refer to:
- Occupancy frequency distribution
- Oakland Fire Department
- Orange Fire Department
- Ogof Ffynnon Ddu, an extensive cave system in South Wales
- Orofaciodigital syndrome
- One Fine Day (U.S. TV series), a 2007–2008 American Internet Protocol television series produced in conjunction with students from a variety of Big Ten Universities
- Open Fixed Document(国家版式文档格式),A fixed document format defined by GB/T 33190-2016 aims to replace PDF in Chinese public institutions.