Our Lady of the Assassins (in Spanish "La virgen de los sicarios") may refer to any of the following articles:
- Our Lady of the Assassins (novel) of the Colombian writer Fernando Vallejo, published by Alfaguara, Bogotá, 1993 in Spanish.
- Our Lady of the Assassins (film), 2000, of the French director Barbet Schroeder, based in the novel by Vallejo.