Rolicyclidine

Rolicyclidine
Clinical data
ATC code	none;
Legal status
Legal status	AU: S9 (Prohibited substance); BR: Class F2 (Prohibited psychotropics); CA: Schedule III; DE: Anlage I (Authorized scientific use only); UK: Class A; US: Schedule I; UN: Psychotropic Schedule I;
Identifiers
	IUPAC name 1-(1-phenylcyclohexyl)pyrrolidine;
CAS Number	2201-39-0;
PubChem CID	62436;
DrugBank	DB01549 ;
ChemSpider	56218 ;
UNII	183O9O9JE3;
KEGG	D12706 ;
ChEBI	CHEBI:60805 ;
CompTox Dashboard (EPA)	DTXSID8046167 ;
Chemical and physical data
Formula	C16H23N
Molar mass	229.367 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1ccccc1C3(N2CCCC2)CCCCC3;
	InChI InChI=1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2 ; Key:FYOWWXMGDATDQY-UHFFFAOYSA-N ;
	(verify)

Rolicyclidine (PCPy) is a dissociative anesthetic that is similar in effects to phencyclidine, but is slightly less potent and has fewer stimulant effects.^[2] It instead produces a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.^[3] Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known.

References

^ Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
^ Kalir A, Edery H, Pelah Z, Balderman D, Porath G (May 1969). "1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity". Journal of Medicinal Chemistry. 12 (3): 473–7. doi:10.1021/jm00303a030. PMID 4977945.
^ DEA Microgram Bulletin, 8, 143, 1975

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[1] Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.

[2] Kalir A, Edery H, Pelah Z, Balderman D, Porath G (May 1969). "1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity". Journal of Medicinal Chemistry. 12 (3): 473–7. doi:10.1021/jm00303a030. PMID 4977945.

[3] DEA Microgram Bulletin, 8, 143, 1975

[2]

[3]

[1]

Clinical data

ATC code	none
Legal status
Legal status	AU: S9 (Prohibited substance) BR: Class F2 (Prohibited psychotropics)^[1] CA: Schedule III DE: Anlage I (Authorized scientific use only) UK: Class A US: Schedule I UN: Psychotropic Schedule I
Identifiers
IUPAC name 1-(1-phenylcyclohexyl)pyrrolidine
CAS Number	2201-39-0
PubChem CID	62436
DrugBank	DB01549^Y
ChemSpider	56218^Y
UNII	183O9O9JE3
KEGG	D12706^Y
ChEBI	CHEBI:60805^Y
CompTox Dashboard (EPA)	DTXSID8046167
Chemical and physical data
Formula	C₁₆H₂₃N
Molar mass	229.367 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c1ccccc1C3(N2CCCC2)CCCCC3
InChI InChI=1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2^Y Key:FYOWWXMGDATDQY-UHFFFAOYSA-N^Y
(verify)

Rolicyclidine

See also

References