Pacific Palisades may refer to:
- Pacific Palisades, Los Angeles, California, a neighborhood located in the Westside of Los Angeles
- Pacific Palisades (TV series), 1997 Aaron Spelling production set in Pacific Palisades, Los Angeles
- Pacific Palisades (film), 1990 French-American comedy film set in Pacific Palisades, Los Angeles
- Pacific Palisades Conservation Area, a region of sandstone cliffs near Pacific, Missouri
- A suburban neighborhood located in Pearl City on the island of Oʻahu in Hawaiʻi