Panther Creek may refer to:
Streams
editFlorida
edit- Panther Creek (Florida), a tributary of East Bay River, near Navarre, Florida
Idaho
edit- Panther Creek (Idaho), a tributary of the Salmon River (Idaho)
Illinois
edit- Panther Creek (Mackinaw River), a tributary of the Mackinaw River
- Panther Creek (North Fork Embarras River), a tributary of the North Fork Embarras River
- Jim Edgar Panther Creek State Fish and Wildlife Area, in Cass County
Iowa
edit- Panther Creek (Iowa), a tributary of the Raccoon River
Missouri
edit- Panther Creek (Blackwater River)
- Panther Creek (Brush Creek tributary)
- Panther Creek (Caldwell County)
- Panther Creek (Cape Girardeau County)
- Panther Creek (East Fork Grand River)
- Panther Creek (James River)
- Panther Creek (Osage Fork Gasconade River)
- Panther Creek (Osage River)
- Panther Creek (Polk County)
New York
editPennsylvania
edit- Panther Creek (Little Schuylkill River), a tributary of the Little Schuylkill River
- Panther Creek (Spring Brook), a tributary of Spring Brook in Spring Brook Township, Lackawanna County
Washington
edit- Panther Creek (Wind River), the river of Panther Creek Falls
West Virginia
edit- Panther Creek (Tug Fork), a stream in West Virginia
Other
edit- Panther Creek Township, Cass County, Illinois
- Panther Creek High School (North Carolina), in Cary
- Panther Creek State Park, in Tennessee
- Panther Creek Consolidated Independent School District, in Valera, Texas
- Panther Creek High School (Valera, Texas), in the above district
- Panther Creek Wind Farm, in Big Spring, Texas