Patrick Walker may refer to:
- Patric Walker (1931–1995), American-born British astrologer
- Patrick Walker (executive), British media executive
- Sir Patrick Walker (MI5 officer) (1932–2021), director general of MI5 1988–1991
- Patrick Gordon Walker (1907–1980), British politician
- Pat Walker (footballer) (born 1959), Irish football manager and former player
- Patrick Walker, British musician, Warning lead singer and guitarist
- Pat Walker (rugby league) (born 1986), English rugby league player
- Pat Walker (philanthropist), American philanthropist