Penicillium parvum is an anamorph species of fungus in the genus Penicillium which was isolated from soil in Papua New Guinea.[1][3][4][5] Penicillium parvum produces ferrichrome siderophores[6][7]
| Penicillium parvum | |
|---|---|
Scientific classification 
| |
| Domain: | Eukaryota |
| Kingdom: | Fungi |
| Division: | Ascomycota |
| Class: | Eurotiomycetes |
| Order: | Eurotiales |
| Family: | Aspergillaceae |
| Genus: | Penicillium |
| Species: | P. parvum
|
| Binomial name | |
| Penicillium parvum Raper, K.B.; Fennell, D.I. 1948[1]
| |
| Type strain | |
| ATCC 10479, CBS 359.48, CSIR 740, FRR 2095, IFO 7732, IMI 040587, NBRC 7732, NRRL 2095, NRRL A-809, QM 1878[2] | |
| Synonyms | |
|
Carpenteles parvum,[1] | |
Phytochemical investigation of the soil microfungus Eupenicillum parvum led to the isolation of two new compounds: a chromone derivative euparvione and a new mycophenolic derivative euparvilactone, as well as thirteen known compounds. Several isolated compounds were evaluated for in vitro binding assays using opioid receptors (subtypes δ, κ, and μ) and cannabinoid receptors (CB1 and CB2). Compound 10 displayed the best selective μ-opioid receptor and CB1 receptor binding affinities showing values of 47% and 52% at a 10 μM concentration, respectively. These findings provide insight into the potential therapeutic utility of this class of compounds.[8]
References
edit- ^ a b c d e MycoBank
- ^ Straininfo of Penicillium parvum
- ^ a b c UniProt
- ^ ATCC
- ^ Hakkō Kenkyūjo (2000). List of cultures: microorganisms. The Institute. ISBN 4891140100.
- ^ Rajeev K. Upadhyay; K.G. Mukerji; B. P. Chamola (2001). Biocontrol Potential and its Exploitation in Sustainable Agriculture: Volume 1: Crop Diseases, Weeds, and Nematodes. Springer Science & Business Media. ISBN 0306464608.
- ^ B.H. Dunford; D. Dolphin; K.N. Raymond; L. Sieker (2012). The Biological Chemistry of Iron: A Look at the Metabolism of Iron and Its Subsequent Uses in Living Organisms Proceedings of the NATO Advanced Study Institute held at Edmonton, Alberta, Canada, August 13 – September 4, 1981. Springer Science & Business Media. ISBN 9400978820.
- ^ León, Francisco; Gao, Jiangtao; Dale, Olivia; Wu, Yunshan; Habib, Eman; Husni, Afeef; Hill, Robert; Cutler, Stephen (2013-11-28). "Secondary Metabolites from Eupenicillium parvum and Their in Vitro Binding Affinity for Human Opioid and Cannabinoid Receptors". Planta Medica. 79 (18): 1756–1761. doi:10.1055/s-0033-1351099. ISSN 0032-0943.
Further reading
edit- Douglas Templeton (2002). Molecular and Cellular Iron Transport Edition. CRC Press. ISBN 0824744179.
- T. R. Swinburne (2012). Iron, Siderophores, and Plant Diseases. Springer Science & Business Media. ISBN 1461594804.
- Peterson, S. W.; Orchard, S. S.; Menon, S. (2011). "Penicillium menonorum , a new species related to P. Pimiteouiense". IMA Fungus. 2 (2): 121. doi:10.5598/imafungus.2011.02.02.02. PMC 3359809. PMID 22679596.