Pleșa may refer to several places in Romania:
- Pleșa, a village in Berești-Meria Commune, Galați County
- Pleșa, a village in the town of Bumbești-Jiu, Gorj County
- Pleșa, a village in Mănăstirea Humorului Commune, Suceava County
- Pleșa (Timiș), a tributary of the Timiș in Caraș-Severin County
- Pleșa, a tributary of the Jiul de Vest in Hunedoara County
- Pleșa, a tributary of the Horezu in Vâlcea County