- October 29: The Philadelphia Phillies win Philadelphia's first major sports championship in twenty-five years after beating the Tampa Bay Rays in the 2008 World Series. (Philadelphia inquirer)
- October 18: The Please Touch Museum reopens in its new home in Memorial Hall. (The Morning Call)
- October 17: Part of a couple charged with an extensive identity theft scheme, Jocelyn Kirsch is sentenced to five years in prison after pleading guilty. (Philadelphia Inquirer)
- October 15: The Philadelphia Phillies beat the Los Angeles Dodgers to win the National League pennant and go to the World Series for the first time since 1993. (Philadelphia Inquirer)
- October 7: WCAU news anchor Lori Delgado resigns amid reports about incidents involved with former anchor Vince DeMentri who has filed a praecipe against Delgado and a WCAU security official. (Philly.com)
