RG1 may refer to:
- Ginsenoside Rg1, a bioactive molecule
- a United Kingdom postcode covering Reading area
- RG-1 (propellant) is a Soviet/Russian rocket propellant similar to RP-1
- R1–RG1 (Rodalies de Catalunya), a commuter rail line in Catalonia, Spain
RG-I may refer to:
- Rhamnogalacturonan I, a type of pectin
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