Rab GTPase-binding effector protein 1 is an enzyme that in humans is encoded by the RABEP1 gene .[ 5] [ 6] It belongs to rabaptin protein family.
^ a b c GRCh38: Ensembl release 89: ENSG00000029725 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020817 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
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^ "Entrez Gene: RABEP1 rabaptin, RAB GTPase binding effector protein 1" .
^ a b c Mattera R, Arighi CN, Lodge R, Zerial M, Bonifacino JS (Jan 2003). "Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex" . The EMBO Journal . 22 (1): 78–88. doi :10.1093/emboj/cdg015 . PMC 140067 . PMID 12505986 .
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^ a b Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M (Apr 1998). "Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5" . The EMBO Journal . 17 (7): 1941–51. doi :10.1093/emboj/17.7.1941 . PMC 1170540 . PMID 9524117 .
^ Xiao GH, Shoarinejad F, Jin F, Golemis EA, Yeung RS (Mar 1997). "The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis" . The Journal of Biological Chemistry . 272 (10): 6097–100. doi :10.1074/jbc.272.10.6097 . hdl :20.500.12613/9244 . PMID 9045618 .
^ Valsdottir R, Hashimoto H, Ashman K, Koda T, Storrie B, Nilsson T (Nov 2001). "Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER" . FEBS Letters . 508 (2): 201–9. doi :10.1016/s0014-5793(01)02993-3 . PMID 11718716 . S2CID 21545088 .
Xiao GH, Shoarinejad F, Jin F, Golemis EA, Yeung RS (Mar 1997). "The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis" . The Journal of Biological Chemistry . 272 (10): 6097–100. doi :10.1074/jbc.272.10.6097 . hdl :20.500.12613/9244 . PMID 9045618 .
Vitale G, Rybin V, Christoforidis S, Thornqvist P, McCaffrey M, Stenmark H, Zerial M (Apr 1998). "Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5" . The EMBO Journal . 17 (7): 1941–51. doi :10.1093/emboj/17.7.1941 . PMC 1170540 . PMID 9524117 .
Neve RL, Coopersmith R, McPhie DL, Santeufemio C, Pratt KG, Murphy CJ, Lynn SD (Oct 1998). "The neuronal growth-associated protein GAP-43 interacts with rabaptin-5 and participates in endocytosis" . The Journal of Neuroscience . 18 (19): 7757–67. doi :10.1523/JNEUROSCI.18-19-07757.1998 . PMC 6793001 . PMID 9742146 .
Swanton E, Bishop N, Woodman P (Dec 1999). "Human rabaptin-5 is selectively cleaved by caspase-3 during apoptosis" . The Journal of Biological Chemistry . 274 (53): 37583–90. doi :10.1074/jbc.274.53.37583 . PMID 10608812 .
Nagelkerken B, Van Anken E, Van Raak M, Gerez L, Mohrmann K, Van Uden N, Holthuizen J, Pelkmans L, Van Der Sluijs P (Mar 2000). "Rabaptin4, a novel effector of the small GTPase rab4a, is recruited to perinuclear recycling vesicles" . The Biochemical Journal . 346 (3): 593–601. doi :10.1042/0264-6021:3460593 . PMC 1220890 . PMID 10698684 .
Hirst J, Lui WW, Bright NA, Totty N, Seaman MN, Robinson MS (Apr 2000). "A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome" . The Journal of Cell Biology . 149 (1): 67–80. doi :10.1083/jcb.149.1.67 . PMC 2175106 . PMID 10747088 .
Korobko IV, Korobko EV, Kiselev SL (Nov 2000). "The MAK-V protein kinase regulates endocytosis in mouse". Molecular & General Genetics . 264 (4): 411–8. doi :10.1007/s004380000293 . PMID 11129044 . S2CID 21231710 .
Zhu Y, Doray B, Poussu A, Lehto VP, Kornfeld S (Jun 2001). "Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor". Science . 292 (5522): 1716–8. Bibcode :2001Sci...292.1716Z . doi :10.1126/science.1060896 . PMID 11387476 . S2CID 9453730 .
Valsdottir R, Hashimoto H, Ashman K, Koda T, Storrie B, Nilsson T (Nov 2001). "Identification of rabaptin-5, rabex-5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER" . FEBS Letters . 508 (2): 201–9. doi :10.1016/S0014-5793(01)02993-3 . PMID 11718716 . S2CID 21545088 .
de Renzis S, Sönnichsen B, Zerial M (Feb 2002). "Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes". Nature Cell Biology . 4 (2): 124–33. doi :10.1038/ncb744 . PMID 11788822 . S2CID 6596498 .
Mattera R, Arighi CN, Lodge R, Zerial M, Bonifacino JS (Jan 2003). "Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex" . The EMBO Journal . 22 (1): 78–88. doi :10.1093/emboj/cdg015 . PMC 140067 . PMID 12505986 .
Mattera R, Puertollano R, Smith WJ, Bonifacino JS (Jul 2004). "The trihelical bundle subdomain of the GGA proteins interacts with multiple partners through overlapping but distinct sites" . The Journal of Biological Chemistry . 279 (30): 31409–18. doi :10.1074/jbc.M402183200 . PMID 15143060 .
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