John Robin Warren AC (11 June 1937 – 23 July 2024) was an Australian pathologist, Nobel laureate, and researcher who is credited with the 1979 re-discovery of the bacterium Helicobacter pylori, together with Barry Marshall.[1] The duo proved to the medical community that the bacterium Helicobacter pylori (H. pylori)[1] is the cause of most peptic ulcers.[1]

Robin Warren
Warren in 2009
Born
John Robin Warren

(1937-06-11)11 June 1937
Died23 July 2024(2024-07-23) (aged 87)
NationalityAustralian
EducationSt Peter's College, Adelaide
Alma materUniversity of Adelaide
Known forDiscovery of Helicobacter pylori
AwardsPaul Ehrlich and Ludwig Darmstaedter Prize (1997)
Nobel Prize in Physiology or Medicine (2005)
Scientific career
FieldsPathologist
InstitutionsRoyal Perth Hospital

Early life and education

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Warren was born 11 June 1937 in North Adelaide. His father, Roger Warren, was a winemaker, and his mother, Helen Warren (née Verco), was a nurse.[2] Warren received his M.B.B.S. degree from the University of Adelaide, having completed his high school education at St Peter's College, Adelaide.

Career

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Warren trained at the Royal Adelaide Hospital and became a Registrar in Clinical Pathology at the Institute of Medical and Veterinary Science (IMVS). There, he worked in laboratory haematology, which generated his interest in pathology.

In 1963, Warren was appointed Honorary Clinical Assistant in Pathology and Honorary Registrar in Haematology at Royal Adelaide Hospital. Subsequently, he lectured in pathology at Adelaide University and then became Clinical Pathology Registrar at the Royal Melbourne Hospital. In 1967, Warren was elected to the Royal College of Pathologists of Australasia and became a senior pathologist at the Royal Perth Hospital, where he spent the majority of his career.

Nobel Prize work

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At the University of Western Australia,Warren along with his colleague Barry J. Marshall, aproved that the bacterium is the infectious cause of stomach ulcers.[3] Warren helped develop a convenient diagnostic test (14
C
-urea breath-test
) for detecting H. pylori in ulcer patients.[4]

In 2005, Warren and Marshall were awarded the Nobel Prize in Medicine.

An Australian documentary was made in 2006 about Warren and Marshall's road to the Nobel Prize, called "The Winner's Guide to the Nobel Prize". He was appointed a Companion of the Order of Australia in 2007.[5]

Asteroid 254863 Robinwarren, discovered by Italian amateur astronomer Silvano Casulli in 2005, was named in his honour.[6] The official naming citation was published by the Minor Planet Center on 22 April 2016 (M.P.C. 99893).[7]

Personal life and death

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Warren married Winifred Theresa Warren (née Williams) in the early 1960s, and together they had five children.[8] Winifred Warren became an accomplished psychiatrist. Following her death in 1997, Warren retired from medicine.[8]

Warren died in Perth, Australia, on 23 July 2024, at the age of 87.[9][10][11]

See also

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References

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  1. ^ a b c "Press Release: The Nobel Prize in Physiology or Medicine 2005". Nobelprize.org. Retrieved 24 March 2018.
  2. ^ Rosenwald, Michael S. (9 August 2024). "J. Robin Warren, Who Proved That Bacteria Cause Ulcers, Dies at 87". The New York Times. Retrieved 10 November 2024.
  3. ^ Marshall BJ, Warren JR (June 1984). "Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration". Lancet. 323 (8390): 1311–5. doi:10.1016/S0140-6736(84)91816-6. PMID 6145023. S2CID 10066001.
  4. ^ Surveyor I, Goodwin CS, Mullan BP, Geelhoed E, Warren JR, Murray RN, Waters TE, Sanderson CR (1989). "The 14
    C
    -urea breath-test for the detection of gastric Campylobacter pylori infection". Med J Aust. 151 (8): 435–9. doi:10.5694/j.1326-5377.1989.tb101252.x. PMID 2593958. S2CID 40191259.
  5. ^ It's an Honour — Companion of the Order of Australia
  6. ^ "254863 Robinwarren (2005 SM4)". Minor Planet Center. Retrieved 3 September 2019.
  7. ^ "MPC/MPO/MPS Archive". Minor Planet Center. Retrieved 3 September 2019.
  8. ^ a b J. Robin Warren on Nobelprize.org  , accessed 11 October 2020
  9. ^ Farewell to a Giant of Pathology and Medicine
  10. ^ "Newsroom - AusBiotech Ltd".
  11. ^ Obituaries, Telegraph (29 July 2024). "Robin Warren, pathologist who identified the true cause of most stomach ulcers – obituary". The Telegraph.
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