Roderick Macleod or MacLeod may refer to:
- Roderick MacLeod (Old Rory) (c. 1500 – c. 1595), chief of Clan MacLeod of Lewis
- Roderick Macleod of Macleod (1573–1626), 15th chief of Clan Macleod
- Roderick Macleod, 2nd of Cadboll (died 1770), Scottish Jacobite and rebel
- Roderick Macleod (physician) (died 1852), Scottish physician
- Roderick Macleod, 4th of Cadboll (1786–1853), Scottish politician
- Roderick Macleod (Alberta politician) (1908–2004), provincial level politician from Alberta, Canada
- Roderick John MacLeod, Lord Minginish (born c. 1953), Scottish lawyer, chairman of the Scottish Land Court since 2014
- Roderick MacLeod (minister) (1754–1815), principal of King's College, Aberdeen, 1800–1815
- Roddy MacLeod (born 1962), Scottish bagpipe player