Romer is a surname. Notable people with the surname include:
- Wolfgang William Romer (1640–1713), Dutch/British military engineer
- Ole Rømer (1644–1710), Danish astronomer
- John Lambertus Romer (1680–1754), British military engineer
- Johann Jacob Roemer (1763–1819), Swiss physician and naturalist
- Michał Józef Römer (1778–1853), politician, writer, and notable member of the Polish-Lithuanian gentry
- Isabella Frances Romer (1798–1852), English travel writer and novelist
- Edward Jan Römer (1806−1878), Polish painter
- Friedrich Adolph Roemer (1809–1869), German geologist
- Emma Romer (1814–1868), British soprano
- Ferdinand von Roemer (1818–1891), German geologist, brother of Friedrich Adolph Roemer
- John Romer (politician) (fl. 1831), 19th century Governor of Bombay
- Alfred Isidore Romer, (1832–1897), Belarusian, Polish and Lithuanian painter, sculptor, carver and medalist, participant of the January Uprising (1863)
- Sir Robert Romer (1840–1918), British judge
- Edward Mateusz Römer (1848–1900), Polish painter
- Mark Romer, Baron Romer (1866–1944), British judge
- Eugeniusz Romer (1871–1954), Polish cartographer
- Lucien von Römer (1873–1965), Dutch physician, botanist and writer
- Helena Romer-Ochenkowska (1875–1947), Polish writer, playwright, opinion journalist, theatre critic and activist
- Michał Pius Römer (1880–1945), Lithuanian lawyer
- Josef “Beppo” Römer (1892–1944), German anti-fascist Freikorps leader and KPD organizer
- Alfred Romer (1894–1973), U.S. paleontologist
- Tadeusz Romer (1894–1978), Polish diplomat and politician
- Sir Charles Romer (1897–1969), British judge
- Charles E. Roemer, II (1923–2012), Louisiana planter, businessman, and politician
- William F. Roemer, Jr. (1926–1996), U.S. FBI agent
- Piet Römer (1928–2012), Dutch actor
- Roy Romer (born 1928), governor of Colorado
- Elizabeth Roemer (born 1929), U.S. astronomer
- John Romer (Egyptologist) (born 1941), British egyptologist
- Buddy Roemer (1943–2021), U.S. politician
- John Roemer (born 1945), U.S. economist
- Kenneth Roemer (born 1945), U.S. scholar of utopian, American, and Native American literature.
- Hanne Rømer (born 1949), Danish composer
- Paul Romer (born 1955), U.S. economist
- Timothy J. Roemer (born 1956), U.S. politician and ambassador
- Christina Romer (born 1958), U.S. economist, chair of the Council of Economic Advisers
- David Romer (born 1958), U.S. economist
- Marcus Romer (born 1961), UK theatre director
- Emile Roemer (born 1962), Dutch politician
- Max Joseph Roemer (1791–1849), German botanist
- Sarah Roemer (born 1984), American actress