S-Glutathionylation is the posttranslational modification of protein cysteine residues by the addition of glutathione, the most abundant and important low-molecular-mass thiol within most cell types.[1]
Protein S-glutathionylation is involved in
- oxidative stress[1]
- nitrosative stress[1]
- preventing irreversible oxidation of protein thiols[1]
- control of cell-signalling pathways by modulating protein function [1]