A Signal-regulatory protein (SIRP) is one of a family of transmembrane glycoproteins involved in immunological signalling, expressed mainly by myeloid cells.[1][2]
| Signal-regulatory protein | |
|---|---|
| Identifiers | |
| Symbol | SRP |
| Membranome | 42 |
Members include :
References
edit- ^ a b c van Beek EM, Cochrane F, Barclay AN, van den Berg TK (December 2005). "Signal regulatory proteins in the immune system". Journal of Immunology. 175 (12): 7781–7. doi:10.4049/jimmunol.175.12.7781. PMID 16339510.
- ^ Barclay AN, Brown MH (June 2006). "The SIRP family of receptors and immune regulation". Nature Reviews. Immunology. 6 (6): 457–64. doi:10.1038/nri1859. PMID 16691243. S2CID 7915923.
- ^ Visser N, Nelemans LC, He Y, Lourens HJ, Corrales MG, Huls G, Wiersma VR, Schuringa JJ, Bremer E (December 2023). "Signal regulatory protein beta 2 is a novel positive regulator of innate anticancer immunity". Frontiers in Immunology. 14: 1287256. doi:10.3389/fimmu.2023.1287256. PMID 38116002.
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