P3 protein

SLC10A3
Identifiers
Aliases	SLC10A3, DXS253E, P3, solute carrier family 10 member 3
External IDs	OMIM: 312090; MGI: 95048; HomoloGene: 10525; GeneCards: SLC10A3; OMA:SLC10A3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	154,490,690 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	73,416,955 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; Descending thoracic aorta; ; skin of leg; ; ascending aorta; ; stromal cell of endometrium; ; right ovary; ; granulocyte; ; decidua; ; skin of abdomen; ; left ovary;
	Top expressed in
	decidua; ; granulocyte; ; zygote; ; seminal vesicula; ; external carotid artery; ; internal carotid artery; ; primary oocyte; ; epithelium of stomach; ; gastrula; ; Ileal epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	symporter activity; bile acid:sodium symporter activity;
Cellular component	membrane; integral component of membrane;
Biological process	response to retinoic acid; transmembrane transport; response to organic substance; bile acid and bile salt transport;
	Sources:Amigo / QuickGO
Orthologs
	8273
	214601
	ENSG00000126903
	ENSMUSG00000032806
	P09131
	P21129
	NM_001142391; NM_001142392; NM_019848
	NM_001256104; NM_145406
	NP_001135863; NP_001135864; NP_062822
	NP_001243033; NP_663381
	Wikidata
View/Edit Human	View/Edit Mouse

P3 protein is a protein that in humans is encoded by the SLC10A3 gene.^[5]^[6]

This gene maps to a GC-rich region of the X chromosome and was identified by its proximity to a CpG island. It is thought to be a housekeeping gene.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000126903 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032806 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chen EY, Zollo M, Mazzarella R, Ciccodicola A, Chen CN, Zuo L, Heiner C, Burough F, Repetto M, Schlessinger D, D'Urso M (Jun 1997). "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci". Hum Mol Genet. 5 (5): 659–68. doi:10.1093/hmg/5.5.659. PMID 8733135.
^ ^a ^b "Entrez Gene: SLC10A3 solute carrier family 10 (sodium/bile acid cotransporter family), member 3".

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Alcalay M, Toniolo D (1988). "CpG islands of the X chromosome are gene associated". Nucleic Acids Res. 16 (20): 9527–43. doi:10.1093/nar/16.20.9527. PMC 338761. PMID 3186440.
Faust CJ, Levinson B, Gitschier J, Herman GE (1992). "Extension of the physical map in the region of the mouse X chromosome homologous to human Xq28 and identification of an exception to conserved linkage". Genomics. 13 (4): 1289–95. doi:10.1016/0888-7543(92)90048-W. PMID 1354645.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000126903 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032806 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8733135-5] Chen EY, Zollo M, Mazzarella R, Ciccodicola A, Chen CN, Zuo L, Heiner C, Burough F, Repetto M, Schlessinger D, D'Urso M (Jun 1997). "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci". Hum Mol Genet. 5 (5): 659–68. doi:10.1093/hmg/5.5.659. PMID 8733135.

[entrez-6] "Entrez Gene: SLC10A3 solute carrier family 10 (sodium/bile acid cotransporter family), member 3".

[5]

[6]

[1]

[2]

[3]

[4]

P3 protein

See also

References

Further reading