Stt3a, catalytic subunit of the oligosaccharyltransferase complex

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STT3A, catalytic subunit of the oligosaccharyltransferase complex is a protein that in humans is encoded by the STT3A gene. [5]

STT3A
Identifiers
AliasesSTT3A, ITM1, STT3-A, TMC, catalytic subunit of the oligosaccharyltransferase complex, STT3 oligosaccharyltransferase complex catalytic subunit A, CDG1WAR, CDG1WAD
External IDsOMIM: 601134; MGI: 105124; HomoloGene: 40617; GeneCards: STT3A; OMA:STT3A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278503
NM_001278504
NM_152713

NM_008408

RefSeq (protein)

NP_001265432
NP_001265433
NP_689926

NP_032434

Location (UCSC)Chr 11: 125.59 – 125.63 MbChr 9: 36.64 – 36.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene is a catalytic subunit of the N-oligosaccharyltransferase (OST) complex, which functions in the endoplasmic reticulum to transfer glycan chains to asparagine residues of target proteins. A separate complex containing a similar catalytic subunit with an overlapping function also exists. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015].

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134910Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032116Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: STT3A, catalytic subunit of the oligosaccharyltransferase complex". Retrieved 2018-07-12.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.