Saint Sylvester or Silvester may refer to:
- Sylvester I (285–335), pope and Christian saint
- New Year's Eve, Saint Silvester's feast day
- Saint Silvester Marathon, street running competition in Brazil
- San Silvestre Vallecana, street running competition in Spain
- St. Sylvester, Schwabing, a church dedicated to the saint
- Saint Sylvester Gozzolini
- St. Silvester, a commune in Switzerland