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The salivarius-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] The salivarius-1 motif occurs in various strains of the species Lactobacillus salivarius, as well as some metagenomic sequences that come from unknown species. salivarius-1 RNAs likely function in trans as small RNAs. While most salivarius-1 RNAs are upstream of protein-coding genes, which could suggest a function as cis-regulatory elements, the downstream gene is often located far away. Curiously, salivarius-1 RNAs are often located nearby to other salivarius-1 RNAs.
| salivarius-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of salivarius-1 RNA | |
| Identifiers | |
| Symbol | salivarius-1 |
| Rfam | RF03030 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
References
edit- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.