San Pascual may refer to:
- Paschal Baylón, a Spanish friar and saint in the Roman Catholic Church
- San Pascual, Batangas in the Philippines
- San Pascual, Masbate in the Philippines
- San Pascual, Ávila in Castile and León, Spain
- San Pascual (Madrid), a ward of Ciudad Lineal district, Madrid, Spain
- San Pascualito, a folk saint venerated in Guatemala and southern Mexico
- San Pascual Pueblo, a former Piro pueblo in New Mexico, United States