Sapphic may refer to:
- Sappho, Greek poet of the 7th century BC who wrote about her attraction to women
- Sapphic stanza, a four line poetic form
- Sapphism, an inclusive umbrella term for attraction or relationships between queer women—whether they identify as lesbian, bisexual, pansexual, asexual, non-binary or trans.
- Sapphic literature, literary subgenre for works featuring relationships between women