Senator Thornton may refer to:
- Daniel I. J. Thornton (1911–1976), Colorado State Senate
- Harry I. Thornton (1834–1895), California State Senate
- John Thornton (U.S. politician) (1846–1917), U.S. Senator from Louisiana from 1910 to 1915
- R. Ewell Thornton (1865–1928), Virginia State Senate
- William L. Thornton (1844–1915), New York State Senate