Series 2 could refer to:
- Apple Watch Series 2, a smart watch by Apple
- Aston Martin Lagonda Series 2, the automobile model
- Aston Martin V8 Series 2, the automobile model
- BMW 2 Series, the automobile model line
- GeForce 2 series, line of nVidia video cards
- Scania 2-series, the truck model line
- GP2 Series, motor racing series
- Super2 Series, motor racing series
- South African Class 6E1, Series 2, electric locomotive series
- Cambrian Series 2, geological series