Serotonin–norepinephrine releasing agent

Further information: serotonin releasing agent and norepinephrine releasing agent

A serotonin–norepinephrine releasing agent (SNRA) is a type of drug which induces the release of serotonin and norepinephrine (and epinephrine) in the body and/or brain.

MBDB, an SNRA.

Norfenfluramine, an SNRA.

Only a few SNRAs are known, examples of which include norfenfluramine, (R)-MDMA, MBDB, and MDAI. Fenfluramine/phentermine (Fen-Phen), a combination formulation of fenfluramine, a serotonin releasing agent, and phentermine, a norepinephrine releasing agent, is a functional SNRA that was formerly used as an appetite suppressant for the treatment of obesity.

A closely related type of drug is a serotonin–norepinephrine reuptake inhibitor (SNRI).

See also

• Monoamine releasing agent
• Serotonin releasing agent
• Norepinephrine releasing agent
• Serotonin–dopamine releasing agent
• Serotonin–norepinephrine–dopamine releasing agent